Francis Rodier

Affiliations

Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC H2X 0A9, Canada.
Institut du Cancer de Montréal (ICM), Montreal, QC H2X 0A9, Canada.
Department of Radiology, Radio-Oncology and Nuclear Medicine, Université de Montréal, Montreal, QC H3C 3J7, Canada.

Publications (25)

Dual Inhibition of Autophagy and PI3K/AKT/MTOR Pathway as a Therapeutic Strategy in Head and Neck Squamous Cell Carcinoma.

Cancers

Avec: Monique Bernard , Guillaume B Cardin , Maxime Cahuzac , Tareck Ayad , Eric Bissada , Louis Guertin , Houda Bahig , Phuc Felix Nguyen-Tan , Edith Filion , Olivier Ballivy , Denis Soulieres , Francis Rodier , Apostolos Christopoulos

Quantifying Senescence-Associated Phenotypes in Primary Multipotent Mesenchymal Stromal Cell Cultures.

Methods in molecular biology (Clifton, N.J.)

Avec: Stéphanie Nadeau , Anastasia Cheng , Inés Colmegna , Francis Rodier

UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections.

Transplantation and cellular therapy

Avec: Maude Dumont-Lagacé , Qi Li , Mégane Tanguay , Jalila Chagraoui , Tibila Kientega , Guillaume B Cardin , Ann Brasey , Assya Trofimov , Cédric Carli , Imran Ahmad , Nadia M Bambace , Léa Bernard , Thomas L Kiss , Jean Roy , Denis-Claude Roy , Sébastien Lemieux , Claude Perreault , Francis Rodier , Simon Frédéric Dufresne , Lambert Busque , Silvy Lachance , Guy Sauvageau , Sandra Cohen , Jean-Sébastien Delisle

mTOR as a senescence manipulation target: A forked road.

Advances in cancer research

Avec: Sarah Saoudaoui , Monique Bernard , Guillaume B Cardin , Nicolas Malaquin , Apostolos Christopoulos , Francis Rodier

Dynamic and scalable assessment of the senescence-associated secretory phenotype (SASP).

Methods in cell biology

Avec: Nicolas Malaquin , Francis Rodier

Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence.

Nature communications

Avec: Hubert Fleury , Nicolas Malaquin , Véronique Tu , Sophie Gilbert , Aurélie Martinez , Marc-Alexandre Olivier , Alexandre Sauriol , Laudine Communal , Kim Leclerc-Desaulniers , Euridice Carmona , Diane Provencher , Anne-Marie Mes-Masson , Francis Rodier

Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging.

JCI insight

Avec: Denise P Muñoz , Steven M Yannone , Anneleen Daemen , Yu Sun , Funda Vakar-Lopez , Misako Kawahara , Adam M Freund , Francis Rodier , Jennifer D Wu , Pierre-Yves Desprez , David H Raulet , Peter S Nelson , Laura J van 't Veer , Judith Campisi , Jean-Philippe Coppé

Senolytic Targeting of Bcl-2 Anti-Apoptotic Family Increases Cell Death in Irradiated Sarcoma Cells.

Cancers

Avec: Julie Lafontaine , Guillaume B Cardin , Nicolas Malaquin , Jean-Sébastien Boisvert , Francis Rodier , Philip Wong

DCBLD1 is associated with the integrin signaling pathway and has prognostic value in non-small cell lung and invasive breast carcinoma.

Scientific reports

Avec: Guillaume B Cardin , Monique Bernard , Francis Rodier , Apostolos Christopoulos

Defining melanoma combination therapies that provide senolytic sensitivity in human melanoma cells.

Frontiers in cell and developmental biology

Avec: Daméhan Tchelougou , Nicolas Malaquin , Guillaume B Cardin , Jordan Desmul , Simon Turcotte , Francis Rodier

DNA Damage- But Not Enzalutamide-Induced Senescence in Prostate Cancer Promotes Senolytic Bcl-xL Inhibitor Sensitivity.

Cells

Avec: Nicolas Malaquin , Arthur Vancayseele , Sophie Gilbert , Laureen Antenor-Habazac , Marc-Alexandre Olivier , Zakia Ait Ali Brahem , Fred Saad , Guila Delouya , Francis Rodier

Biomarkers of cardiometabolic complications in survivors of childhood acute lymphoblastic leukemia.

Scientific reports

Avec: Sophia Morel , Pauline Léveillé , Mariia Samoilenko , Anita Franco , Jade England , Nicolas Malaquin , Véronique Tu , Guillaume B Cardin , Simon Drouin , Francis Rodier , Sarah Lippé , Maja Krajinovic , Caroline Laverdière , Daniel Sinnett , Geneviève Lefebvre , Emile Levy , Valérie Marcil

Assessing Functional Roles of the Senescence-Associated Secretory Phenotype (SASP).

Methods in molecular biology (Clifton, N.J.)

Avec: Nicolas Malaquin , Véronique Tu , Francis Rodier

Single Nucleotide Polymorphism rs6942067 Is a Risk Factor in Young and in Non-Smoking Patients with HPV Negative Head and Neck Squamous Cell Carcinoma.

Cancers

Avec: Guillaume B Cardin , Monique Bernard , Houda Bahig , Phuc Felix Nguyen-Tan , Olivier Ballivy , Edith Filion , Denis Soulieres , Pierre Philouze , Tareck Ayad , Louis Guertin , Eric Bissada , Francis Rodier , Apostolos Christopoulos

Autophagy drives fibroblast senescence through MTORC2 regulation.

Autophagy

Avec: Monique Bernard , Bing Yang , Francis Migneault , Julie Turgeon , Mélanie Dieudé , Marc-Alexandre Olivier , Guillaume B Cardin , Mostafa El-Diwany , Katy Underwood , Francis Rodier , Marie-Josée Hébert

Non-canonical ATM/MRN activities temporally define the senescence secretory program.

EMBO reports

Avec: Nicolas Malaquin , Marc-Alexandre Olivier , Aurélie Martinez , Stéphanie Nadeau , Christina Sawchyn , Jean-Philippe Coppé , Guillaume Cardin , Frédérick A Mallette , Judith Campisi , Francis Rodier

NCOR1 Sustains Colorectal Cancer Cell Growth and Protects against Cellular Senescence.

Cancers

Avec: Stéphanie St-Jean , Ariane Cristina De Castro , Mia Lecours , Christine Jones , Nathalie Rivard , Francis Rodier , Nathalie Perreault , François Boudreau

Targeting IKKε in Androgen-Independent Prostate Cancer Causes Phenotypic Senescence and Genomic Instability.

Molecular cancer therapeutics

Avec: Sophie Gilbert , Benjamin Péant , Nicolas Malaquin , Véronique Tu , Hubert Fleury , Kim Leclerc-Desaulniers , Francis Rodier , Anne-Marie Mes-Masson , Fred Saad

A defective splicing machinery promotes senescence through MDM4 alternative splicing.

Aging cell

Avec: Mathieu Deschênes , Mathieu Durand , Marc-Alexandre Olivier , Alicia Pellerin-Viger , Francis Rodier , Benoit Chabot

Copper-Catalyzed Coupling between

The Journal of organic chemistry

Avec: Vincent Boquet , Chris Sauber , Raphaël Beltran , Vincent Ferey , Fabien Rodier , Pierre Hansjacob , Cédric Theunissen , Gwilherm Evano

Homologous recombination-mediated irreversible genome damage underlies telomere-induced senescence.

Nucleic acids research

Avec: Sabrina Ghadaouia , Marc-Alexandre Olivier , Aurélie Martinez , Tibila Kientega , Jian Qin , Patrick Lambert-Lanteigne , Guillaume B Cardin , Chantal Autexier , Nicolas Malaquin , Francis Rodier

Targeted Anti-Cancer Provascular Therapy Using Ultrasound, Microbubbles, and Nitrite to Increase Radiotherapy Efficacy.

Bioconjugate chemistry

Avec: Simon Michon , Francis Rodier , François T H Yu

Radiotherapy on-chip: microfluidics for translational radiation oncology.

Lab on a chip

Avec: Rodin Chermat , Maryam Ziaee , David Y Mak , Elena Refet-Mollof , Francis Rodier , Philip Wong , Jean-François Carrier , Yuji Kamio , Thomas Gervais

Premature thymic functional senescence is a hallmark of childhood acute lymphoblastic leukemia survivorship.

Blood cancer journal

Avec: Tibila Kientega , Sophie Marcoux , Jessica Bourbonnais , Jade Montpetit , Maxime Caru , Guillaume B Cardin , Nathalie Arbour , Valérie Marcil , Daniel Curnier , Caroline Laverdière , Daniel Sinnett , Francis Rodier

Guidelines for minimal information on cellular senescence experimentation in vivo.

Cell

Avec: Mikolaj Ogrodnik , Juan Carlos Acosta , Peter D Adams , Fabrizio d'Adda di Fagagna , Darren J Baker , Cleo L Bishop , Tamir Chandra , Manuel Collado , Jesus Gil , Vassilis Gorgoulis , Florian Gruber , Eiji Hara , Pidder Jansen-Dürr , Diana Jurk , Sundeep Khosla , James L Kirkland , Valery Krizhanovsky , Tohru Minamino , Laura J Niedernhofer , João F Passos , Nadja A R Ring , Heinz Redl , Paul D Robbins , Francis Rodier , Karin Scharffetter-Kochanek , John M Sedivy , Ewa Sikora , Kenneth Witwer , Thomas von Zglinicki , Maximina H Yun , Johannes Grillari , Marco Demaria

Réseau de co-auteurs

Guillaume B Cardin 11 collaborations

Nicolas Malaquin 11 collaborations

Marc-Alexandre Olivier 6 collaborations

Monique Bernard 5 collaborations

Apostolos Christopoulos 4 collaborations

Véronique Tu 4 collaborations

Tibila Kientega 3 collaborations

Sophie Gilbert 3 collaborations

Aurélie Martinez 3 collaborations

Tareck Ayad 2 collaborations

Eric Bissada 2 collaborations

Louis Guertin 2 collaborations

Houda Bahig 2 collaborations

Phuc Felix Nguyen-Tan 2 collaborations

Edith Filion 2 collaborations

Olivier Ballivy 2 collaborations

Denis Soulieres 2 collaborations

Stéphanie Nadeau 2 collaborations

Hubert Fleury 2 collaborations

Kim Leclerc-Desaulniers 2 collaborations

Anne-Marie Mes-Masson 2 collaborations

Judith Campisi 2 collaborations

Jean-Philippe Coppé 2 collaborations

Philip Wong 2 collaborations

Fred Saad 2 collaborations

Caroline Laverdière 2 collaborations

Daniel Sinnett 2 collaborations

Valérie Marcil 2 collaborations

Maxime Cahuzac 1 collaboration

Anastasia Cheng 1 collaboration

Inés Colmegna 1 collaboration

Maude Dumont-Lagacé 1 collaboration

Qi Li 1 collaboration

Mégane Tanguay 1 collaboration

Jalila Chagraoui 1 collaboration

Ann Brasey 1 collaboration

Assya Trofimov 1 collaboration

Cédric Carli 1 collaboration

Imran Ahmad 1 collaboration

Nadia M Bambace 1 collaboration

Léa Bernard 1 collaboration

Thomas L Kiss 1 collaboration

Jean Roy 1 collaboration

Denis-Claude Roy 1 collaboration

Sébastien Lemieux 1 collaboration

Claude Perreault 1 collaboration

Simon Frédéric Dufresne 1 collaboration

Lambert Busque 1 collaboration

Silvy Lachance 1 collaboration

Guy Sauvageau 1 collaboration

Sandra Cohen 1 collaboration

Jean-Sébastien Delisle 1 collaboration

Sarah Saoudaoui 1 collaboration

Alexandre Sauriol 1 collaboration

Laudine Communal 1 collaboration

Euridice Carmona 1 collaboration

Diane Provencher 1 collaboration

Denise P Muñoz 1 collaboration

Steven M Yannone 1 collaboration

Anneleen Daemen 1 collaboration

Yu Sun 1 collaboration

Funda Vakar-Lopez 1 collaboration

Misako Kawahara 1 collaboration

Adam M Freund 1 collaboration

Jennifer D Wu 1 collaboration

Pierre-Yves Desprez 1 collaboration

David H Raulet 1 collaboration

Peter S Nelson 1 collaboration

Laura J van 't Veer 1 collaboration

Julie Lafontaine 1 collaboration

Jean-Sébastien Boisvert 1 collaboration

Daméhan Tchelougou 1 collaboration

Jordan Desmul 1 collaboration

Simon Turcotte 1 collaboration

Arthur Vancayseele 1 collaboration

Laureen Antenor-Habazac 1 collaboration

Zakia Ait Ali Brahem 1 collaboration

Guila Delouya 1 collaboration

Sophia Morel 1 collaboration

Pauline Léveillé 1 collaboration

Mariia Samoilenko 1 collaboration

Anita Franco 1 collaboration

Jade England 1 collaboration

Simon Drouin 1 collaboration

Sarah Lippé 1 collaboration

Maja Krajinovic 1 collaboration

Geneviève Lefebvre 1 collaboration

Emile Levy 1 collaboration

Pierre Philouze 1 collaboration

Bing Yang 1 collaboration

Francis Migneault 1 collaboration

Julie Turgeon 1 collaboration

Mélanie Dieudé 1 collaboration

Mostafa El-Diwany 1 collaboration

Katy Underwood 1 collaboration

Marie-Josée Hébert 1 collaboration

Christina Sawchyn 1 collaboration

Guillaume Cardin 1 collaboration

Frédérick A Mallette 1 collaboration

Stéphanie St-Jean 1 collaboration

Ariane Cristina De Castro 1 collaboration

Mia Lecours 1 collaboration

Christine Jones 1 collaboration

Nathalie Rivard 1 collaboration

Nathalie Perreault 1 collaboration

François Boudreau 1 collaboration

Benjamin Péant 1 collaboration

Mathieu Deschênes 1 collaboration

Mathieu Durand 1 collaboration

Alicia Pellerin-Viger 1 collaboration

Benoit Chabot 1 collaboration

Vincent Boquet 1 collaboration

Chris Sauber 1 collaboration

Raphaël Beltran 1 collaboration

Vincent Ferey 1 collaboration

Fabien Rodier 1 collaboration

Pierre Hansjacob 1 collaboration

Cédric Theunissen 1 collaboration

Gwilherm Evano 1 collaboration

Sabrina Ghadaouia 1 collaboration

Jian Qin 1 collaboration

Patrick Lambert-Lanteigne 1 collaboration

Chantal Autexier 1 collaboration

Simon Michon 1 collaboration

François T H Yu 1 collaboration

Rodin Chermat 1 collaboration

Maryam Ziaee 1 collaboration

David Y Mak 1 collaboration

Elena Refet-Mollof 1 collaboration

Jean-François Carrier 1 collaboration

Yuji Kamio 1 collaboration

Thomas Gervais 1 collaboration

Sophie Marcoux 1 collaboration

Jessica Bourbonnais 1 collaboration

Jade Montpetit 1 collaboration

Maxime Caru 1 collaboration

Nathalie Arbour 1 collaboration

Daniel Curnier 1 collaboration

Mikolaj Ogrodnik 1 collaboration

Juan Carlos Acosta 1 collaboration

Peter D Adams 1 collaboration

Fabrizio d'Adda di Fagagna 1 collaboration

Darren J Baker 1 collaboration

Cleo L Bishop 1 collaboration

Tamir Chandra 1 collaboration

Manuel Collado 1 collaboration

Jesus Gil 1 collaboration

Vassilis Gorgoulis 1 collaboration

Florian Gruber 1 collaboration

Eiji Hara 1 collaboration

Pidder Jansen-Dürr 1 collaboration

Diana Jurk 1 collaboration

Sundeep Khosla 1 collaboration

James L Kirkland 1 collaboration

Valery Krizhanovsky 1 collaboration

Tohru Minamino 1 collaboration

Laura J Niedernhofer 1 collaboration

João F Passos 1 collaboration

Nadja A R Ring 1 collaboration

Heinz Redl 1 collaboration

Paul D Robbins 1 collaboration

Karin Scharffetter-Kochanek 1 collaboration

John M Sedivy 1 collaboration

Ewa Sikora 1 collaboration

Kenneth Witwer 1 collaboration

Thomas von Zglinicki 1 collaboration

Maximina H Yun 1 collaboration

Johannes Grillari 1 collaboration

Marco Demaria 1 collaboration